Updated: Aug 12, 2026
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| Certification Vendor: | Association of Clinical Research Professionals (ACRP) |
| Exam Name: | ACRP Certified Professional Exam |
| Exam Number: | ACRP-CP |
| Available Languages: | English |
| Passing Score: | Scaled score of 600 or higher |
| Exam Price: | $435 – $600 |
| Exam Duration: | 180 minutes |
| Related Certifications: | ACRP Certified Clinical Research Associate (CCRA) ACRP Certified Clinical Research Coordinator (CCRC) ACRP Certified Principal Investigator (CPI) |
| Certificate Validity Period: | 3 years |
| Exam Format: | Multiple-choice questions, Recall questions, Scenario-based questions |
| Real Exam Qty: | 125 (100 scored, 25 pre-test) |
| Recommended Training: | ACRP Official Training Resources |
| Exam Registration: | ACRP Official Registration |
| Sample Questions: | ACRP ACRP-CP Sample Questions |
| Exam Way: | Online remote proctored or in-person at PSI test centers |
| Pre Condition: | 3,000 hours verifiable clinical research work experience; or 1,500 hours plus clinical research degree |
| Official Syllabus URL: | https://acrpnet.org/certification/acrp-cp-certification |
| Section | Weight | Objectives |
|---|---|---|
| Professionalism and Ethical Practice | 15% | - Continuous improvement
|
| Data Management and Informatics | 17% | - Data reporting
|
| Regulatory and Compliance Requirements | 17% | - Compliance procedures
|
| Clinical Study Operations | 15% | - Site management
|
| Study Design and Conduct | 17% | - Study planning
|
| Ethical and Participant Safety Considerations | 19% | - Clinical care and management of research participants
|
1. A study sponsor approaches a facility about participating in their research study. The study sponsor requires use of social media as its sole method of recruitment. The site knows their institutional IRB/IEC does not approve of social media recruiting. How should the site respond?
A) Recruit for the study without use of social media.
B) Rely on the sponsor to notify the IRB/IEC.
C) Decline the study.
D) Use a central IRB/IEC.
2. A protocol requires participants to take IP for 6 months. The protocol allows for any participants who are noncompliant to be replaced by enrolling additional participants, except if it is due to an AE. The investigator has enrolled 12 participants.
The status of the enrolled participants is as follows:
* 3 participants were withdrawn due to noncompliance
* 1 participant withdrew consent after experiencing severe nausea
* 1 participant had to discontinue IP for an unscheduled hospitalization
* 1 participant who is not returning for visits
* 2 participants completed the 6 months of treatment
* 4 participants currently on IP
How many participants should be replaced?
A) 4 participants
B) 6 participants
C) 3 participants
D) 5 participants
3. During a monitoring visit, a CRA notices that a piece of equipment required for the study needs to be serviced. Who is responsible for addressing this problem?
A) CRC
B) CRA
C) Sponsor
D) PI
4. At a close-out visit, which document should be retained only at the site?
A) Subject identification code list
B) Treatment allocation
C) IP accountability
D) Final trial close-out monitoring report
5. Preliminary evidence suggests a low-dose anti-cancer drug given for a short period of time may reduce the risk of developing cancer in patients who are at increased risk for developing cancer. The drug has potentially serious side effects. What is the MOST important question to consider before designing a clinical trial to test this hypothesis?
A) How willing are current patients to participate in a trial with potentially serious side effects?
B) How likely are patients at high risk of cancer going to develop cancer during the study?
C) How effective is the drug at treating patients that have been previously diagnosed with cancer?
D) How does the risk of developing cancer compare to the anticipated side effects from the drug?
Solutions:
| Question # 1 Answer: C | Question # 2 Answer: C | Question # 3 Answer: D | Question # 4 Answer: A | Question # 5 Answer: D |
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