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Last Updated: Sep 11, 2026

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ACRP ACRP-CP Exam Syllabus Topics:

SectionObjectives
Topic 1: Participant Safety and Protection- Informed consent process
- Safety reporting and adverse events
Topic 2: Clinical Research Foundations- Good Clinical Practice (GCP) principles
- Ethical conduct in clinical trials
Topic 3: Data and Quality Management- Clinical data management principles
- Quality assurance and quality control
Topic 4: Study Operations- Study planning and initiation
- Study conduct and oversight
Topic 5: Regulatory Compliance- Audit and inspection readiness
- Regulatory documentation and submissions

ACRP Certified Professional Sample Questions:

Question #1

Which of the following reports should be retained in participant charts?

  • A. DSMB/IDMC reports
  • B. IRB/IEC progress reports
  • C. Lab reports
  • D. Safety reports
Answer: C

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Question #2

AEs that occur between study visits of a clinical trial should be evaluated by the:

  • A. Subject's primary care physician
  • B. Principal Investigator
  • C. Study pharmacovigilance physician
  • D. Medical monitor
Answer: B

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Question #3

A root cause analysis should be:

  • A. Written by the investigator.
  • B. Specific to a clinical trial.
  • C. Focused on issues of non-compliance.
  • D. Validated before use in a CAPA.
Answer: C

Explanation: Only visible for Test4Sure members. You can sign-up / login (it's free).

Question #4

Who is responsible for defining, establishing, and allocating all trial-related duties and functions prior to initiating a trial?

  • A. IRB/IEC
  • B. CRO
  • C. Sponsor
  • D. Investigator
Answer: C

Explanation: Only visible for Test4Sure members. You can sign-up / login (it's free).

Question #5

Who should vote during the IRB/IEC review and discussion process?

  • A. All members who were involved in the review and discussion
  • B. All IRB/IEC members and non-member experts
  • C. All IRB/IEC members
  • D. All members who were involved in the review and discussion and non-member experts
Answer: A

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